TRPV4 agonist-1
4(3H)-Quinazolinone, 8-fluoro-3-[4-(4-fluorophenoxy)phenyl]-2-(4-methyl-1-piperazinyl)-, hydrochloride (1:1)
CAS: 2314467-60-0
Molecular Formula: C25H23ClF2N4O2
TRPV4 agonist-1 - Names and Identifiers
| Name | 4(3H)-Quinazolinone, 8-fluoro-3-[4-(4-fluorophenoxy)phenyl]-2-(4-methyl-1-piperazinyl)-, hydrochloride (1:1) |
| Synonyms | OUN67600 TRPV4 agonist RPV4 agonist-1 TRPV4 agonist-1 OUN67600(TRPV4 agonist-1) |
| CAS | 2314467-60-0 |
TRPV4 agonist-1 - Physico-chemical Properties
| Molecular Formula | C25H23ClF2N4O2 |
| Molar Mass | 484.93 |
| Solubility | Soluble in DMSO |
| Storage Condition | -20℃ |
| Use | OUN67600, is a Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonist as Regulators of Chondrogenic Differentiation. |
TRPV4 agonist-1 - Reference
| Reference Show more | Atobe M, Nagami T, Muramatsu S, Ohno T, Kitagawa M, Suzuki H, Ishiguro M, Watanabe A, Kawanishi M. Discovery of Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonists as Regulators of Chondrogenic Differentiation: Identification of Quinazolin-4(3 H)-ones and in Vivo Studies on a Surgically Induced Rat Model of Osteoarthritis. J Med Chem. 2019 Feb 14;62(3):1468-1483. doi: 10.1021/acs.jmedchem.8b01615. Epub 2019 Jan 28. PMID: 30629441. |
TRPV4 agonist-1 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.062 ml | 10.311 ml | 20.621 ml |
| 5 mM | 0.412 ml | 2.062 ml | 4.124 ml |
| 10 mM | 0.206 ml | 1.031 ml | 2.062 ml |
| 5 mM | 0.041 ml | 0.206 ml | 0.412 ml |
Last Update：2024-01-02 23:10:35
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